| AVERA DIALYSIS - BROOKINGS CCN 433510 | BROOKINGS | 5 ★ | Non-profit |
| AVERA DIALYSIS - WAGNER CCN 433512 | WAGNER | 5 ★ | Non-profit |
| AVERA ST MARYS HOSPITAL CCN 432305 | PIERRE | 5 ★ | Non-profit |
| MID-DAKOTA DIALYSIS OF SANFORD HEALTH CCN 433502 | CHAMBERLAIN | 5 ★ | Non-profit |
| AVERA DIALYSIS - MITCHELL CCN 433511 | MITCHELL | 4 ★ | Non-profit |
| AVERA GREGORY HEALTHCARE CTR DIALYSIS CCN 432308 | GREGORY | 4 ★ | Non-profit |
| BLACK HILLS DIALYSIS - EAGLE BUTTE CCN 432501 | EAGLE BUTTE | 4 ★ | Profit |
| BLACK HILLS DIALYSIS - PINE RIDGE CCN 432508 | PINE RIDGE | 4 ★ | Profit |
| DaVita Moccasin Creek Dialysis CCN 432515 | ABERDEEN | 4 ★ | Profit |
| DaVita Rosebud Dialysis CCN 432504 | ROSEBUD | 4 ★ | Profit |
| PRAIRIE LAKES HEALTHCARE SYSTEM CCN 432300 | WATERTOWN | 4 ★ | Non-profit |
| SANFORD HEALTH - DIALYSIS UNIT CCN 432303 | Sioux Falls | 4 ★ | Non-profit |
| SISSETON SATELLITE DIALYSIS CCN 433505 | SISSETON | 4 ★ | Non-profit |
| AVERA SACRED HEART - YANKTON DIALYSIS CCN 432306 | YANKTON | 3 ★ | Non-profit |
| AVERA ST LUKES HOSPITAL CCN 432302 | ABERDEEN | 3 ★ | Non-profit |
| DaVita Sioux Falls Community Dialysis CCN 432503 | SIOUX FALLS | 3 ★ | Profit |
| HURON REGIONAL MEDICAL CTR CCN 432301 | HURON | 3 ★ | Non-profit |
| SANFORD USD MEDICAL CTR - HEMODIALYSIS CCN 432312 | SIOUX FALLS | 3 ★ | Non-profit |
| SHARPS CORNER CCN 432514 | PORCUPINE | 3 ★ | Profit |
| FRESENIUS KIDNEY CARE DAKOTA DUNES CCN 432516 | DAKOTA DUNES | 2 ★ | Profit |
| AVERA DIALYSIS MILBANK CCN 433514 | MILBANK | — | Non-profit |
| AVERA DIALYSIS- SIOUX FALLS CCN 433515 | Sioux Falls | — | Non-profit |
| MADISON DIALYSIS OF SANFORD HEALTH CCN 433507 | MADISON | — | Non-profit |
| Monument Health Dialysis LLC Rapid City CCN 432518 | RAPID CITY | — | Non-profit |
| Monument Health Dialysis LLC Spearfish CCN 432517 | SPEARFISH | — | Non-profit |
| VA MEDICAL CENTER - HOT SPRINGS CCN 432507 | HOT SPRINGS | — | Non-profit |
